動物體溫測量膠囊,小動物體溫遙測系統(tǒng)是一款可連續(xù)監(jiān)測、記錄并無線傳輸核心體溫信號的微型膠囊。大動物可其經(jīng)口腔攝入進入體內(nèi),通過胃、腸道,后由肛門排出;小動物可進行皮下植入。

使用簡單方便,廣泛用于多種科研域。

適用于多種動物,如:大鼠、小鼠、比格犬、兔子等。

體溫膠囊的主要特點:
體積小巧,食用方便,對機體無損害;
實時連續(xù)無創(chuàng)監(jiān)測;
無線無導(dǎo)管測量,測試對象亦無需實時佩戴監(jiān)測器,實現(xiàn)無任何限制測量方案;
膠囊內(nèi)置存儲記憶功能,可存儲多達2000組數(shù)據(jù),無需擔(dān)心數(shù)據(jù)丟失;
監(jiān)測器可同時監(jiān)測3枚膠囊數(shù)據(jù),且自身可多7臺并聯(lián),實現(xiàn)高通量測量;

主要技術(shù)參數(shù):
測量參數(shù):使用溫度25-45℃,精確度0.2℃,采樣頻率30Hz(可設(shè)定),內(nèi)部可存儲2000組數(shù)據(jù);
傳輸參數(shù):傳輸距離1-3m,傳輸頻率433Hz;
規(guī)格參數(shù):17.7*8.9mm,重1.7g;
可同時監(jiān)測并顯示3只動物體內(nèi)膠囊的傳輸,并可通過PC/MAC觀察分析;
每臺監(jiān)測器可存儲80000組數(shù)據(jù);

應(yīng)用1:體溫調(diào)節(jié)研究
監(jiān)測以下三組大鼠的核心體溫在麻醉后的變化趨勢:
預(yù)熱至40℃(PW40, n=17);預(yù)熱至高于基線體溫1%(PW1%, n = 17);無預(yù)熱(NW, n = 17);
系統(tǒng)優(yōu)勢:
1持續(xù)的核心溫度控制
2.實時、后驗的數(shù)據(jù)恢復(fù)
3.可得到個體的體溫調(diào)節(jié)數(shù)據(jù)

相關(guān)文獻:
· Laperrousaz et al., (2018) Lipoprotein Lipase Expression in Hypothalamus is involved in the Central Regulation of Thermogenesis and the Response to Cold Exposure
· Meyer et al., (2017) Body Temperature Measurements for Metabolic Phenotyping in Mice
· Rufiange et al., (2020) Pre-warming before general anesthesia with isoflurane delays the onset of hypothermia in rats
應(yīng)用2:動物生理學(xué)⸺時間生物學(xué)和睡眠研究
植入到非人靈長類腹膜的膠囊收集到的數(shù)據(jù)
系統(tǒng)優(yōu)勢:
1.長時間核心體溫監(jiān)控
2.實時數(shù)據(jù)采集和后驗數(shù)據(jù)恢復(fù)
3.個體核心體溫監(jiān)測
相關(guān)論文:
· Tattersall et al., (2016) Novel energy-saving strategies to multiple stressors in birds: the ultradian regulation of body temperature
· Schulze et al., (2018) Body temperature of bitches in the first week after parturition measured by ingestible loggers
· Guisle et al., (2020) Circadian and sleep/wake-dependent variations in tau phosphorylation are driven by temperature