其他產(chǎn)品及廠家

EchinatinRetrochalcone；刺甘草查爾酮
echinatin disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria, inhibits dnp-atpase activity while
更新時(shí)間:2025-11-04
BIM-23190 aceate
bim-23190 aceate, a somatostatin analog, a selective agonist of sstr2 and sstr5. bim-23190 can be used in cancer and acromegaly studies.
更新時(shí)間:2025-11-04
Azido-PEG4-azideAzido-PEG4-azide
azido-peg4-azide is a peg-based protac linker that can be used to synthesize protacs.
更新時(shí)間:2025-11-04
Phellopterin
phellopterin is a partial agonist of the central benzodiazepine receptors in vitro. phellopterin shows a cytotoxic effect on raw264.7 cell at the concentration from 40 to 400 μm. phellopterin reduce tnf-alpha-induced vcam-1 expression through regulation o
更新時(shí)間:2025-11-04
BefotertinibD-0316；Befotertinib
befotertinib (d-0316) is the third-generation egfr tyrosine kinase inhibitor. befotertinib can be used for the research of egfr t790m-positive non-small cell lung cancer (nsclc).
更新時(shí)間:2025-11-04
Neoliquiritin
neoliquiritin may possess ytotoxiciy and tumor-specificity.
更新時(shí)間:2025-11-04
Nitrofen
nitrofen is a selective contact herbicide. nitrofen is a retinal dehydrogenase and protoporphyrinogen oxidase inhibitor [1] [2] .
更新時(shí)間:2025-11-04
EST73502
est73502 is an agonist of μ-opioid receptor(ki = 64 nm) agonist and an antagonist of σ1 receptor (ki = 118 nm). est73502 displays antinociceptive activity.
更新時(shí)間:2025-11-04
Kaurenoic acid異貝殼杉烯酸；kaur-16-en-18-oic acid；Kauren-19-Oic Acid；kaurenoate
kaurenoic acid has anti-inflammatory potential in acetic acid-induced colitis, decreases in mda level. kaurenoic acid exerts a uterine relaxant effect acting principally through calcium blockade and in part, by the opening of atp-sensitive potassium chann
更新時(shí)間:2025-11-04
Boc-Asp(OMe)-fluoromethyl ketoneBoc-Asp(OMe)-FMK；Boc-Asp(OMe)-fluoromethyl ketone
boc-asp(ome)-fluoromethyl ketone is a broad range caspase inhibitor that inhibits fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of il-8 [1] [2] .
更新時(shí)間:2025-11-04
Isobavachin
isobavachin can facilitate mouse es cells differentiating into neuronal cells.
更新時(shí)間:2025-11-04
Jatrorrhizine藥根堿；neprotin；Yatrorizine
jatrorrhizine is a protoberberine alkaloid isolated from enantia chlorantha (annonaceae) and other species. it was found to have antimicrobial and antifungal activity. it binds and noncompetitively inhibits monoamine oxidase (ic50 4 micromolar for mao-a a
更新時(shí)間:2025-11-04
Isavuconazonium sulfate
isavuconazonium sulfate is hydrolyzed by plasma esterases to yield the active moiety isavuconazole. isavuconazole binds to and inhibits the fungal cytochrome p450 family enzyme lanosterol 14-alpha-demethylase (cyp51), which catalyzes the demethylation of
更新時(shí)間:2025-11-04
γ-Glu-Gly acetate
γ-glu-gly aceate is a human lipid metabolite that is acetate for γ-glutamine dipeptide.
更新時(shí)間:2025-11-04
PATULIN散毒素；棒曲霉素；Claviform；Clavacin；Expansin
patulin is a mycotoxin produced by a variety of molds commonly found in rotting apples, including aspergillus and penicillium.
更新時(shí)間:2025-11-04
Methyl L-histidinate dihydrochlorideL-組氨酸甲酯二鹽酸鹽；L-Histidine methyl ester dihydrochloride
inhibition of histidine decarboxylase in sprague-dawley rat stomach assessed as decrease in 14co2 production with activty value of 1.8 μm
更新時(shí)間:2025-11-04
H-HomoArg-OH.HClL-高精氨酸鹽酸鹽；L-Homoarginine hydrochloride；NSC 145416；L(+)-Homoarginine hydrochloride
l-homoarginine is a specific inhibitor of liver-type alkaline phosphatase.
更新時(shí)間:2025-11-04
BenzoinBenzoylphenylcarbinol；安息香
the main uses of benzoin are as a precursor to benzil, which is a photoinitiator.
更新時(shí)間:2025-11-04
C-Type Natriuretic Peptide (CNP) (1-22), human acetateC-Type Natriuretic Peptide (CNP) (1-22), human
c-type natriuretic peptide (cnp) (1-22), human acetate is an agonist of natriuretic peptide receptor b (npr-b), an endothelial-derived relaxant and growth inhibitory factor. c-type natriuretic peptide (cnp) (1-22), human acetate inhibits camp synthesis s
更新時(shí)間:2025-11-04
CID5721353BCL6 inhibitor
cid5721353 is a b-cell lymphoma 6 inhibitor (bcl6 inhibitor) that disrupts bcl6/corepressor complexes in vitro and in vivo, and was shown to bind the critical site within the btb groove.
更新時(shí)間:2025-11-04
Choline Fenofibrate非諾貝特膽堿；Trilipix；ABT-335
choline fenofibrate is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity.
更新時(shí)間:2025-11-04
RadiprodilRGH-896
radiprodil (rgh-896) is an orally active and selective nmda nr2b receptors antagonist. it was a potential treatment of neuropathic pain associated with diabetic peripheral neuropathy (dpnp).
更新時(shí)間:2025-11-04
Asapiprant
asapiprant (s-555739) is a potent and selective dp1 receptor antagonist (ki: 0.44 nm). it exhibited high affinity and selectivity for the dp1 receptor.
更新時(shí)間:2025-11-04
lp-211 is a brain penetrant selective agonist for a 5-ht7 receptor (ki: 0.58 nm), and >300-fold selectivity over the 5-ht1a receptor.
更新時(shí)間:2025-11-04
2,5-PYRIDINEDICARBOXYLIC ACID
2,5-pyridinedicarboxylic acid is used in the preparation of new derivatives as antiviral agents.
更新時(shí)間:2025-11-04
Volinanserin氟利色林；MDL100907；M 100907
volinanserin (mdl 100907) is a potent and selective antagonist of the serotonin receptor 5-ht2 (ki: 0.36 nm) and shows 300-fold selectivity for 5-ht2 receptor over 5-ht1c, alpha-1 adrenergic and sigma receptors.
更新時(shí)間:2025-11-04
Bepridil hydrochlorideCERM 1978；鹽酸芐普地爾
bepridil is a calcium channel blocker and also inhibits na+/ca2+ exchange (ncx), sodium channels and cardiac sarcolemmal katp channels.
更新時(shí)間:2025-11-04
TP0463518
tp-0463518 is a highly potent hif prolyl hydroxylase (phd) inhibitor (ic50s: 13 nm and 18 nm for human and rat phd2, respectively).
更新時(shí)間:2025-11-04
CK1-IN-1PUN51207
ck1-in-1, compound 1c reported in patent wo2015119579a1, is a casein kinase 1 (ck1) inhibitor. it has ic50s of 15 nm, 16 nm, 73 nm for ck1δ, and ck1ε, p38σ mapk, respectively.
更新時(shí)間:2025-11-04
Prulifloxacin普盧利沙星；Pruvel；NM441；AF 3012
prulifloxacin is a broad-spectrum fluoroquinolone antibiotic. it inhibits bacterial dna synthesis by inhibiting the activity of bacterial dna topoisomerase ii and iv.
更新時(shí)間:2025-11-04
BSJ-03-123
bsj-03-123 is a potent, cdk6-selective small-molecule degrader.
更新時(shí)間:2025-11-04
Letermovir萊莫維韋；MK-8828；AIC246
letermovir (aic246) is a novel anti-cmv compound (ec50: about 5 nm in fibroblast cells). it targets the pul56 subunit of the viral terminase complex.
更新時(shí)間:2025-11-04
BMS 599626 2HCl (873837-23-1(HCl))AC480 dihydrochloride
bms-599626 (ac480) is a selective inhibitor of her1 and her2 (ic50s: 20 nm and 30 nm), ~8-fold less potent to her4, >100-fold to lck, vegfr2, c-kit, met, etc.
更新時(shí)間:2025-11-04
GeA-69
gea-69 (gea69) is a selective and allosteric parp14 macrodomain 2 (md2) inhibitor (kd: 0.86 μm in itc assays).
更新時(shí)間:2025-11-04
Q203Telacebec；IAP6
q203 is a novel potent anti-tuberculosis agent targeting cytochrome b subunit qcrb and inhibits m. tuberculosis h37rv (mic50: 2.7 nm).
更新時(shí)間:2025-11-04
GSK2983559 active metaboliteRIPK2 inhibitor 1；RIPK2-IN-1；GSK2983559
gsk 2983559 (rip2 kinase inhibitor 1) is a potent, selective receptor-interacting protein-2 (rip2) kinase inhibitor.
更新時(shí)間:2025-11-04
DDR1-IN-2DDR1 inhibitor 7rh
ddr1-in-2 (ddr1 inhibitor 7rh) is a potent, selective, atp-competitive discoidin domain receptor 1 (ddr1) inhibitor (ic50: 6.8 nm in cell-free kinase assays).
更新時(shí)間:2025-11-04
ULK-101
ulk-101 is a potent and selective ulk1 inhibitor ( ic50s: 8.3/30 nm for ulk1/ulk2). it can suppress autophagy.
更新時(shí)間:2025-11-04
DDD107498 succinate琥珀酸DDD107498；MMV121；M 5717；DDD498
ddd107498 has a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the plasmodium parasite. it targets translation elongation factor 2 (eef2).
更新時(shí)間:2025-11-04
BI-1347
bi-1347 is a potent, selective inhibitor of cdk8/cyclinc (ic50: 1 nm). it shows tumor growth inhibition in an in vivo xenograft model.
更新時(shí)間:2025-11-04
BranebrutinibBMS986195
bms986195 is a potent, covalent inhibitor of bruton´s tyrosine kinase (btk), >5,000-fold selective over all kinases outside of the tec family (ic50 <1 nm for btk).
更新時(shí)間:2025-11-04
BI-3802
bi-3802 is a highly potent bcl6 degrader and inhibits the bric-à-brac (btb) domain of bcl6 with an ic50 value of ≤3 nm. bi-3802 induces the polymerization of bcl6 and promotes bcl6 degration depended on e3 ligase siah1. bi-3802 has antitumor activity[1][2
更新時(shí)間:2025-11-04
AZD3229
azd3229 is a potent pan-kit mutant inhibitor for the treatment of gastrointestinal stromal tumors. it demonstrates potent single-digit nm growth inhibition across a broad cell panel.
更新時(shí)間:2025-11-04
PD158780
pd 158780 reversibly inhibits auto and transphosphorylation of all four members of the erbb receptor superfamily: egfr, erbb2, erbb3, and erbb4 (ic50s: 8μm, 49 nm, 52 nm, and 52 nm in cell assay).
更新時(shí)間:2025-11-04
PDE10-IN-1SEP-0372814
pde10-in-1 is pde10-in-1 inhibitor extracted from patent wo 2013192273 a1, for treating cns and metabolic disorders.
更新時(shí)間:2025-11-04
RO4987655RG7167；CH4987655
ro4987655 is an orally active and highly selective mek inhibitor (ic50: 5.2 nm for mek1/mek2).
更新時(shí)間:2025-11-04
ML216CID-49852229
ml-216 is a small molecule inhibitor of blm helicase (ic50: 1.8 μm). it showed 28-fold selective against the related helicases recq1, recq5, and e. coli uvrd (ic50s > 50 μm).
更新時(shí)間:2025-11-04
GlumetinibSCC244
glumetinib (scc 244) is a novel potent and selective inhibitor of c-met kinase (ic50: 0.42 nm).
更新時(shí)間:2025-11-04
γ-GTL-谷氨酸 5-(3-甲酸-4硝基苯胺)銨鹽；H-GLA(PNA)-OH
γ-gt is used as a synthetic substrate for gamma-glutamyltransferase (ggt) to determine ggt activity.
更新時(shí)間:2025-11-04
T-5224
t-5224 is a transcription factor c-fos/ap-1 inhibitor, which specifically inhibits the dna binding activity of c-fos/c-jun without affecting other transcription factors.
更新時(shí)間:2025-11-04

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